Tentative Program


Program:  Wednesday, June 13, 2018


Location:          Portofino Hotel and Marina

                        260 PORTOFINO WAY

                        REDONDO BEACH, CA 90277


7:00 pm             Welcome Reception



Program:  Thursday, June 14, 2018



8:00 am                        Breakfast, Registration, Check-In


8:45 am                        Opening Ceremony, Welcome & Announcements

                         Alejandro Almarza 


 Keynote Lecture:


 9:00 am                       Enabling Precision Medicine through Engineering

                                    Ali Khademhosseini


 10:00 am                     Break



Podium Session 1:      Animal Models

10:30 am                      The Temporomandibular Joint of the Domestic Dogs (Canis Lupus

Familiaris) in Health and Disease

Lin A, Vapniarsky N, Cissell DD, Verstraete FJM, Ting V,

Hatcher DC, Arzi B

10:45 am                      Microstructural Changes in the TMJ Bone and Cartilage are

Preceded by Early Upregulation of Joint Hypoxia and Catabolic

Factors After TMJ Loading that Causes Pain in the Rat

Sperry MM, Troche HR, Winkelstein BA, Granquist EJ

11:00 am                      Temporomandibular Joint Pathology in Wild Carnivores in the

Western United States

Verstraete FJM, Arzi B

11:15 am                      Regional and Disease-related Differences in Properties of the Equine

Temporomandibular Joint Disc

Guerrero Cota JM, Leale DM, Arzi B, Cissell DD


11:30 am                      Networking (Poster) Session 


Transzygomatic coronoidectomy and autologous fat placement as a

treatment for pseudoankylosis of the temporomandibular joint

Tekin U, Koçyiğit D, Özgül O


Strategy of Temporomandibular Joint Cartilage Regeneration via

Endogenous Progenitor Cell Homing

Seol D, Song I, Kendrick DE, Chiphet K, Lehman A, Salem AK, Martin JA, Shin K


In Vivo Regenerative Potential of Various Soft Polymeric Scaffolds in

Osteochondral TMJ Defects

Chin AR, Taboas J, Gao J, Wang, Y, Almarza AJ


Orofacial Pain Assessment of Rats With Bite-Raising Splints

Li W, Pineda-Fairas JB, Gold MS, Almarza AJ



12:00 pm                      Lunch



Podium Session 2:      TMJ TISSUE ENGINEERING PART 1                      

1:00 pm                        Fabrication of a Polycaprolactone and Hyaluronic Acid Multi-Material

Regenerative Condylar Implant for Temporomandibular Joint


Wyman OM, Detamore MS 

1:15 pm                        TMJ Condylar Cartilage Regeneration by Scaffold-free MSC-Chondrocyte

Cell Sheet: An In-vitro Study

Hu Y, Zhou G, He D

1:30 pm                        Subcutaneous Implantation of Collagen Scaffolds with MSCs:

The Effect of Angiostatin

Helgeland E, Pedersen T, Mustafa K, Rosén A 


1:45 pm                       Break



Podium Session 3:      BIOMECHANICS                      

2:00 pm                        Characteristics of the TMJ Biomechanical Environment During Function

Colombo V, Gallo LM, Gonzalez YM, Iwasaki LR,

Markovà M, Nickel JC

2:15 pm                        Characterization of the Trabecular Bone Tissue within the Mandible Ramus

- An Innovative Method and Statistical Results

Mesnard M, Teschke M, Supernak M, Duarte R, Ramos A

2:30 pm                        A Novel Combined Rigid Body – Finite Element Model for the

Investigation of Temporomandibular Joint Loads

Sagl B, Piehslinger E, Kundi M, Schimd-Schwap M, Stavness I 

2:45 pm                        Break



Podium Session 4:      TOTAL JOINT PROSTHETICS

3:00 pm                        Serum Metal Levels in Maxillofacial Reconstructive Surgery

Patients. A Pilot Study

Mercuri LG, Miloro MJ, Skipor AK, Jacobs JJ, Sukotjo C, Mathew MT

3:15 pm                        Bespoke 3D Printed TMJ Prosthesis

Fink S, Dimitroulis G

3:30 pm                        A New Concept and Design for an Alloplastic Total TMJ Prosthesis

Using PEEK LT1 20% BA

Genovesi W, Comenale IC, Lordes Pereira W, Faro GG


3:45 pm                        Break



Podium Session 5:      TMJ TISSUE ENGINEERING PART 2

4:00 pm                        Scaffold-free Cartilage Cell Sheet Combined with Bone-phase

BMSCs-scaffold Regenerate Osteochondral Construct in

Mini-pig Model

Wang F, Hu Y, He D, Zhou G, Ellis E

4:15 pm                        In vivo Modeling and Repair of TMJ disc Thinning and

Partial Perforation Using Scaffold-free Biomimetic

Tissue-engineered Implants

Vapniarsky N, Huwe LW, Arzi B, Houghton MK, Wong ME,

Wilson JW, Hatcher DC, Hu JC, Athanasiou KA

4:30 pm                        Stem Cell Derived Methods for Temporomandibular Joint Regeneration

Ruscitto A, Embree M


4:45 pm                        Close


6:00 pm                        Dinner


Program:  Friday, June 15, 2018


8:00 am                        Breakfast, Registration, Check-In

Keynote Lecture:

8:30 am                       Biologic Responses to TJR Implant Debris: What are Innate

and Adaptive Immune Responses to TMJR Implant Debris

and why do they matter?

                                    Nadim James Hallab

9:30 am                       Break 


Podium Session 1:      CLINICAL STUDIES 

10:00 am                      PRP in the therapy of TMD. Evaluation of pain in 5 years follow up study

Machon V, Levorova J

10:15 am                      EMG Measurements Reveal Abnormal Masticatory Muscle Coordination

in TMD Patients

Tartaglia G, Gizdulich A, Silva R, Connelly ST

10:30 am                      Is General Joint Hypermobility Associated with Altered Extra Cellular Matrix

Protein Concentrations in the Temporomandibular Joint?

Ulmner M, Sugars R, Weiner CK, Lund B 

10:45 am                      Break


Podium Session 2:      DEVELOPMENTAL BIOLOGY

11:00 am                      Hormone-Receptor-MMP Axis in the Targeted Degradation of TMJ

Fibrocartilage and Subchondral Bone

Kapila S

11:30 am                      On the Way to the Progenitor Cells of Mandibular Condylar Cartilage: 

Zone-Specific Microarray Study

Basudan AM, Yang YQ

11:45 am                      Regulation of Bone Morphogenetic Protein 2 in the Postnatal Growth and

Development of the Mandibular Condylar Cartilage

O’Brien MH, Dutra EH, Chen P-J, Yadav S

12:00 pm                      Lunch



1:00 pm                        Outcome Analysis of Mandibular Patient Specific Joint Replacements in

TMJ Ankylosis and Tumour: A Prospective Analysis

Mehrotra D

1:15 pm                        Temporomandibular Joint Chondromatosis: A Difficult Diagnosis

Levorova J, Machon V

1:30 pm                        Estrogen Inhibits Lubricin Expression in Baboon TMJ Synovial Cells

  Perez L, Phelix CF, Millican L, LeBaron RG

1:45 pm                        Break 


Podium Session 4:      BIOLOGIC TREATMENTS

2:15 pm                        The Effects of Long-term Intermittent Administration of PTH on the

Mandibular Condylar Cartilage and Subchondral Bone

Dutra EH, O’Brien MH, Chen P-J, Yadav S

2:30 pm                        Articular Disc: Development Guided Regeneration

Weekes K, Pal D, Pryce B, Lam P, Schweitzer, Johnstone B

2:45 pm                        The effects of Parathyroid Hormone and Bisphosphonate on the Cartilage

and the Subchondral Bone of the Temporomandibular Joint

Chen P-J, Dutra EH, O’Brien MH, Yadav S

3:00 pm                        Discussion of Day’s Topics

3:30 pm                        Closing Remarks